Congratulations, you just had your first pathology test, but certainly not your last. The testing of blood, urine and tissue continues throughout a person’s life-cycle.

And it’s a good thing too. Pathology tests are there to pick up on any health concerns nice and early, when they are at their most treatable.

Whatever stage of life you’re at – from being freshly minted to being longer in the tooth – pathology tests are there to help you monitor the inner workings of your body for optimal health.

We run through five tests everyone is likely to have through their lifetime.

Babies | Heel prick test

‘Hey, I didn’t ask for this!’ This is true, sorry fresh baby, but the heel prick test is very important. Taken 48-72 hours after birth, the heel prick test is looking for several conditions:

• Phenylketonuria (PKU) – a condition in which the liver can’t breakdown the amino acid phenylalanine (a building block of protein) and if left untreated can lead to intellectual disability
• Hypothyroidism – the thyroid helps regulate your metabolism. An underactive thyroid doesn’t produce enough hormones and can significantly impact intellectual development and a baby’s growth
• Cystic fibrosis – this condition leads to the production of too much mucus, which clogs the lungs and pancreas, preventing them from functioning properly
• Medium Chain Acyl CoA Dehydrogenase (MCAD) Deficiency– this condition results in inability of the body to completely break down fat. If untreated, it may be life-threatening during common childhood illnesses
• Congenital Adrenal Hyperplasia-an altered ability of the adrenal gland to produce hormones that may affect the baby’s metabolism, response to infection, ability to regulate salt levels and sex characteristics
• Various metabolic disorders – involving amino acid, organic acid and fatty acid oxidation, these disorders can have serious and even fatal effects if not treated

All ages | Full Blood Examination

The no-frills, all-rounder of the blood testing world, the full blood examination (FBE) or full blood count (FBC) is an exam you might have at various stages and for various reasons:

• Anaemia – a low red blood cell count may indicate anaemia
• Various organ diseases – a high red blood cell count may indicate heart, lung or kidney disease, low numbers of white blood cells may indicate liver or spleen disorders
• Leukaemia – high levels of white blood cells may point to leukaemia
• Eclampsia – a high haematocrit count may indicate eclampsia
• Iron deficiency – smaller sized red blood cells may indicate iron deficiency

Middle-age | HbA1c or type 2 diabetes test

Anyone around middle-age will want to speak to their doctor about whether they should be having this test, with diabetes growing at enormous rates across the world.

If you are over 35, have a waist circumference over 100cms (95 for some ethnic groups), or exercise less than 2.5 hours a week, you will want to seriously consider this test.

A person can go for seven years without showing any symptoms of diabetes, during which time it can be causing serious damage to your kidneys, heart, eyes and extremities.

Later middle age: cholesterol

By the time you’re past the half-way mark of life, there’s a good chance you’ve dispatched your fair share of cheeses, lasagnes and choc-tops and might want to check your cholesterol.

The cholesterol test looks for several types of lipids:

• Low-density lipoprotein (LDL) cholesterol – also known as ‘bad cholesterol’, a high level of LDL cholesterol is linked to heart disease and stroke
• High-density lipoprotein (HDL) cholesterol – this good cholesterol helps clean your arteries from fatty build-ups. High is good.
• Triglycerides – high triglycerides can be a pointer to cardiovascular disease or diabetes.

Older age: urine and stool tests

Examining poo and wee is not just for children and comedians. A lot can be determined about someone’s health by looking at urine and stool samples.

Technically these are two types of tests that we’ve briefly outlined below:

• Urinalysis– like the FBE, a lot can be determined by a urine test, or urinalysis. Conditions which can be picked up through a urine test include urinary tract infections (UTIs), kidney disorders, liver disease, or diabetes.
• Bowel cancer screening – for Australian citizens between the ages of 50 and 74, the federal government sends a free bowel cancer screening test kit for a stool sample to be taken at home. If caught early, 90% of bowel cancer cases can be successfully treated.

Of course, the above list of tests is by no means comprehensive. There are a multitude of pathology tests performed every day to help detect medical conditions and to help monitor the treatment of those who already have medical conditions.

Medical scientist and Pathology Awareness Australia ambassador, David Nielsen explains the importance of pathology testing through the life cycle.

‘A lot of people’s experience with medicine is usually with a doctor at the local GP clinic or at a hospital.

‘But there is a whole world of medical diagnosis going on behind the scenes in pathology labs. Every year there are 500 million tests conducted in Australia,’ said Mr Nielsen.

‘And while pathology accounts for just 3% of the annual healthcare budget, 70% of medical treatment decisions rely on pathology.’

The post From cradle to grave: five pathology tests you will likely have through your life first appeared on Know Pathology Know Healthcare.

When Karyn gave birth to Ashlee,  she conducted pathology testing for her baby and discovered Ashlee had Cystic Fibrosis where testing has played a pivotal role in Ashlee’s healthcare ever since.

Karyn is now able to view the world of pathology from the other side too. Since taking up an admin job at a pathology provider she sees every day how pathology helps thousands of other families just like her own.

“I can’t remember a time in Ashlee’s life when she wasn’t undergoing regular pathology tests to monitor her condition. She was diagnosed at five weeks old. It took six long weeks in hospital and three operations until we were finally able to take our beautiful daughter home.

Over the years we learned about the condition and how best to manage it. But then when Ashlee was 21 she underwent a double lung transplant. Less than a year later we were back in the hospital for a second transplant after the new lungs had started failing.

The operations were done in Melbourne which meant that on top of the indescribable fear of watching our daughter go through such a huge procedure we had the added stress (not to mention financial burden) of having to relocate to Melbourne for four months each time.”

Eight years on and Karyn is still relying on pathology to monitor her daughter’s health. Ashlee is now 30 and requires monthly tests to monitor the potential side effects of the medication she has to take to avoid her body rejecting the lungs and to monitor her Cystic Fibrosis.

“Without pathology my daughter would not be alive. Instead she has grown into an amazing and inspirational young woman. Although she still has her ups and downs we’re not taking anything for granted.”

Dr Melody Caramins is a pathologist specialising in genetics;

“Cystic Fibrosis is the most common genetically acquired, chronic condition in Australia. Although there is currently no cure, life-expectancy and life quality for people with Cystic Fibrosis have both increased significantly in the past twenty years.

From the heel prick test that diagnoses the condition just minutes after a baby is born, to the regular testing to monitor a person’s condition, pathology tests are invaluable in caring for people with Cystic Fibrosis.”

If you have a story of how pathology has helped you or someone you love we want to hear from you, email info@knowpathology.com.au

The post “Thanks to pathology my little girl is now an amazing young woman” first appeared on Know Pathology Know Healthcare.